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Plague: Recognition, Treatment, and Prevention - PMC
WEBDec 26, 2017 · Laboratory evidence includes detection by bacterial culture and antigen, antibody, and nucleic acid testing. Antibiotics, including streptomycin and gentamicin, are recommended to effectively treat the different types of plague.
- Author: Ruifu Yang
- DOI: 10.1128/JCM.01519-17
- Publish Year: 2017
- Publication: J Clin Microbiol. 2018 Jan; 56(1): e01519-17.
See results only from ncbi.nlm.nih.govYersinia pestis: mechanis…
Introduction. Three Yersinia species are known to be pathogenic to humans: …
Plague vaccine: recent pr…
Until now, no licensed plague vaccine is available. Prophylactic vaccination …
Antibiotic Therapy of Plag…
The data obtained in vitro and from animal models, case reports and the few …
An open-label, randomized, …
The primary objective of the trial is to test the hypothesis that ciprofloxacin …
Finding a Clinical Trial | N…
This is a searchable registry and results database of federally and privately …
Antibiotics for treating plagu…
clinical studies reporting outcomes for plague treatment in adults and children …
The efficacy, safety, and im…
We performed a systemic review of available randomised controlled trials …
Chapter 12 Plague vaccin…
Two clinical trials were reported for the rF1-V plague vaccine. The first trial was …
Resources for Clinicians | Plague | CDC
Learn how to diagnose and treat plague based on clinical signs, symptoms, and exposure history. Find out the recommended antibiotics, laboratory tests, and i…
- Plague should be considered in any patient with clinical signs of plague and a recent history of residence in or travel to the western United States or other plague endemic areas. Bubonic plag…
- Estimated Reading Time: 8 mins
- Published: Feb 25, 2022
A new generation needle- and adjuvant-free trivalent plague …
WEBJan 29, 2021 · A plague vaccine with a fusion cassette of YscF, F1, and LcrV encoding genes in an adenovirus-5 vector (rAd5-YFV) is evaluated for efficacy and immune …
- Your treatment plan may include one or more of these options.Treatment options include antibiotics and supportive care.MedicationSpecialist To ConsultSource: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
- People also askWhat are the treatments for bubonic plague?
Dr. Anet Varghese
Doctor of Medicine (MBBS) · 1 years of exp
If the diagnosis is suspected on clinical and epidemiological grounds, treatment must be started as soon as, or even before, samples have been collected for laboratory diagnosis. Streptomycin (1 g twice daily) or gentamicin (1 mg/kg 3 times daily) is the drug of choice. Tetracycline (500 mg 4 times daily) and chloramphenicol (12. 5 mg/kg 4 times daily) are alternatives. Fluoroquinolones (ciprofloxacin and levofloxacin) may be as effective but there is less clinical experience. Treatment may also be needed for acute circulatory failure, DIC and hypoxia.Q&A: Plaguemicrosoftstart.msn.com An open-label, randomized, non-inferiority trial of the efficacy and ...
WEBAug 17, 2020 · All drugs in use for treating plague are registered based on experimental data and anecdotal evidence, and no regimen currently recommended is supported by a …
Preparing for the next plague | Nature Biotechnology
WEBNov 19, 2021 · Moderna has already announced that it has preclinical data on a combination flu and COVID-19 vaccine, which will be going into clinical trials next year, …
Death and Clinical Trials in the Plague Years - The ASCO Post
WEBApr 21, 2022 · Detailed analyses of the cause of death revealed a major discordance between the arms, with COVID-19–related deaths dominating the umbralisib/ublituximab …
Plague vaccine: recent progress and prospects | npj Vaccines
WEBFeb 18, 2019 · Direct inhalation of aerosolized Y. pestis can result in an extremely lethal form of primary pneumonic plague. 1 The short incubation period (1–3 days) of …
WEBTreatment of plague with gentamicin or doxycycline in a randomized clinical trial in Tanzania. Clin Infect Dis. 2006 42(5):614-21. 2Boulanger LL, Ettestad P, Fogarty JD, …
WEBThe WHO mapping tool currently registers 17 plague vaccine candidates under development, by private and public-sector laboratories. Two of these candidates have …
Blueprint - World Health Organization (WHO)
WEBJan 8, 2018 · In 2018, WHO convened experts in epidemiology, regulatory, preclinical and clinical vaccine evaluation trials, regulatory affairs, statistics, and mathematical …
Plague - Diagnosis and treatment - Mayo Clinic
WEBApr 20, 2023 · A health care provider will likely make a probable diagnosis of plague based on: Symptoms. Possible exposure to the disease during recent outdoor activity or travel. …
Dynavax doses first subject in Phase II plague vaccine trial
WEBVishnu Priyan September 13, 2022. Dynavax Technologies has dosed the first subject in a Phase II clinical trial of a recombinant plague (rF1V) vaccine, along with the company’s …
HD Trialfinder - Huntington's Disease Society of America
WEBHD Trialfinder is a clinical trials matching service: a way for individuals with Huntington’s disease, caregivers, healthy volunteers, and physicians to connect with current research …
A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin ...
WEBNov 18, 2010 · Study Description. Go to. Brief Summary: Plague is a severe, life-threatening disease. Plague occurs in focal locations worldwide, but over 95% of …
Home - ClinicalTrials.gov
WEBClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world. Explore 495,518 …
Bisoprolol in Patients With Chronic Obstructive Pulmonary …
WEB5 days ago · In this randomized clinical trial, among patients with COPD at risk of exacerbations, bisoprolol compared with placebo did not decrease the number of self …
Second Phase 3 clinical trial again shows dupilumab lessens …
WEB3 days ago · Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug — dupilumab — that showed rapid and sustained …
More than one-half of patients with Crohn's disease treated with …
WEB3 days ago · About the VIVID-1 Clinical Trial Program VIVID-1 was a Phase 3, randomized, double-blind, treat-through study that evaluated the safety and efficacy of mirikizumab …
Results from first human clinical trial offer promising early results ...
WEB1 day ago · Alzheimer's disease is the most common cause of dementia, affecting more than 55 million people worldwide. ... This clinical trial represents the first instance of …
11 clinical trials that will shape medicine in 2022 - Nature
WEBDec 10, 2021 · 230 Altmetric. Metrics. Nature Medicine asks leading researchers to name their most anticipated clinical trial for 2022, from CRISPR and psilocybin to oncolytic …
Reporting and Representation of Participant Demographic …
WEBMay 15, 2024 · Communities of color in the United States, particularly Black and Latino persons, are disproportionately affected by Alzheimer’s disease and related dementias …
Did Body Lice Spread Bubonic Plague? Research Suggests the …
WEB10 hours ago · The bubonic plague killed an estimated 25 million people in Europe—about one-third of the continent’s population—during a pandemic known as the Black Death in …
A breakthrough for lupus treatment? Study explores CAR T-cell …
WEBMay 13, 2024 · CAR T-cell therapy clinical trial at UC Davis Health. The new, industry-funded clinical trial with Cabaletta Bio is evaluating CABA-201, an investigational …
Second Phase 3 clinical trial again shows dupilumab lessens …
WEB21 hours ago · Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation. ScienceDaily . Retrieved May 23, 2024 from …
Bisoprolol in Patients With Chronic Obstructive Pulmonary …
WEBImportance: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Observational studies report that β-blocker use may be …
Eli Lilly's mirikizumab shows promise in Crohn's disease trial
WEB2 days ago · Credit: Jennie Book / Shutterstock. Eli Lilly has reported promising results from the Phase III VIVID-1 study of mirikizumab in treating moderately to severely active …
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